Skip to content
Geelong Eye Health logoGeelong Eye Health

Eye drops not working for your dry eyes? Why might a proper assessment help?

If eye drops are not working—or only help briefly—the next step is to understand why. Natural tears are a complex, changing mixture that drops cannot fully reproduce.

At a glance

Key points

  • Eye drops can support the tear film, but they cannot reproduce all the functions of natural tears.
  • Persistent symptoms may involve the eyelids, oil glands, overnight exposure, allergy or another eye-surface problem.
  • A useful assessment connects your history with examination and imaging rather than relying on symptoms alone.
  • Sudden pain, light sensitivity or vision change needs urgent assessment rather than routine dry-eye care.

Your tears are way more complex than eye drops

Eye drops are useful, but they cannot reproduce the full complexity of natural tears.

Natural tears are extraordinarily complex. They contain roughly 2,000 components, compared with about a dozen principal ingredients in typical eye drops. Those natural components are like an orchestra: it is not enough for the instruments to be present; they have to work in harmony.

The exact number of components in natural tears depends on what scientists count and how samples are collected. The TFOS DEWS II Tear Film Report reports more than 1,500 identified tear proteins and more than 200 peptides. Tears also contain many lipids, mucins, electrolytes and small metabolites. A 2023 human tear-proteome analysis drew on 1,543 proteins identified in healthy human tears; showing the scale of the tear film's complexity. However, an eye-drop formulation can reproduce only selected properties.

Some tear components lubricate the eye. Others help tears spread and maintain a smooth optical surface. The tear film also supports defence, immune signalling, tissue repair and control of evaporation. A drop may support one of these functions, but it cannot fully replace your own tear film.

Schematic showing proteins, peptides, lipids, mucins, electrolytes and metabolites working together in the tear film
“The most important thing is to educate patients about their eyes.”

At Geelong Eye Health, Leigh shows infrared video and photographs on a large screen. Patients can see the findings instead of simply receiving a product name.

Why might eye drops stop helping?

Lubricating drops can provide temporary relief, but they may not address every contributor to dry-eye symptoms. Mild cases may respond well to this simple approach, but when the effect fades quickly, an assessment can investigate what may be disturbing the eye surface.

An unstable tear film can increase evaporation and make the tears more concentrated. These changes can contribute to inflammation and surface stress. Surface damage and poor wetting can then make the tear film even less stable.

Circular diagram of tear-film instability, evaporation and concentration, inflammation and surface damage

What can the dry eye symptoms hide?

“Dry eye” can describe many conditions. You may wake up with red eyes or notice tired, weary eyes. Or, you may experience burning, itching, watering, glare, light sensitivity or a foreign-body sensation. Or, you may have a sensation of grittiness or a feeling of something in your eye. Your vision may clear after blinking and then blur again.

Your story is part of the examination

Your history gives the examination context. Timing, screens, airflow, contact lenses, medicines, sleep, hormones, work, health history and previous procedures can all change the picture.

The eyelid oil glands provide clues

Leigh gently assesses the meibomian glands and examines their secretions. Clear, olive-oil-like secretion provides one clue. Little or no expression provides another.

The eyelids may not seal completely overnight

Some people wake with worse symptoms because their eyelids do not close fully during sleep. Leigh assesses eyelid closure as one possible contributor to overnight exposure. Morning symptoms do not always call for another drop.

The surface can be shown, not just described

Leigh displays infrared video and clinical photographs on a large screen. Patients can then see what he sees. The images provide evidence, and Leigh explains how the findings fit together.

Dry-eye symptoms may be something else

Burning, watering, redness, itch, grittiness and fluctuating blur are symptoms, not diagnoses. Allergy, infection, tear-drainage problems and exposure can overlap with or resemble dry eye.

The first plan is not the final word

If management is not working, Leigh returns to the findings. He checks what has changed and how practical the plan has been. Reassessment then guides the next adjustment.

Leigh Plowman examining a patient at a slit-lamp microscope
A slit-lamp examination lets Leigh inspect the eyelids and ocular surface closely.

The oil test: what comes from the eyelid glands?

The meibomian glands sit along the eyelids and supply oil to the tear film. If they are not producing enough oil, or if their secretion is of poor quality, the tear film loses stability even when tear volume is adequate.

Tear quantity alone doesn't determine eye comfort. The tear film must also spread evenly, remain stable and protect the surface between blinks. Poor oil-gland function destabilises the tear film and accelerates evaporation.

Meibomian-gland dysfunction can contribute to evaporative dry eye. Reduced tear production and mixed patterns also occur, as discussed in the TFOS DEWS III diagnostic framework.

Morning symptoms may be caused by how you sleep

Incomplete eyelid closure during sleep can contribute to dry-eye symptoms. When the lids do not seal, part of the eye surface may remain exposed overnight. Normal blinking cannot redistribute the tear film during sleep.

To check if the eyelid seal is adequate, we use a small light to check the eyelid seal following the procedure outlined in the TFOS DEWS III Diagnostic Methodology Report .

However, morning redness does not mean that everyone sleeps with their eyes open. The eyelid-seal check is also not a home diagnostic test.

Leigh using ocular-surface imaging equipment during an eye assessment

See what the optometrist sees

Imaging becomes useful when someone explains it

Infrared video and photographs are used to make an invisible-feeling problem visible. The images can document a baseline and support comparison over time.

The machine does not replace judgement. The value lies in linking the image to your history, the examination and a plan you understand.

What happens when the first plan does not work?

When the first plan does not work, we return to the diagnosis and findings. We check what has changed and adjust the plan. The treatment may have been difficult to use consistently. Screens, airflow, sleep or another exposure may have changed. The first explanation may also have been incomplete. The approach we follow is consistent with the approach described in the TFOS DEWS III Management and Therapy Report.

The daily burden

“When their eyes are bad, people talk about thinking about their eyes all the time.”

The aim is management that reduces that burden—not a promise that a chronic condition can never return.

When should you move beyond self-treatment?

When artificial tears have not provided useful relief after about a month, consider an assessment. Reaching for drops every 15–30 minutes, or every hour, also suggests that the root cause needs to be identified and treated.

When you come for an assessment, bring every eye product you use, or clear photos of the labels. Note how often you use each product and how long the effect lasts. Do not stop prescribed eye medicine without speaking to the prescribing clinician.

A sudden change is not routine dry eye

We need to distinguish chronic patterns from going from “nothing yesterday” to marked redness, light sensitivity or blurred vision today. New severe pain, sudden or persistent vision change, injury, chemical exposure or a foreign body also needs urgent professional assessment. If symptoms are severe or sight is suddenly affected, review the clinic's emergency eye-care guidance and seek emergency care rather than waiting for an online booking.

The question to ask before buying the next bottle

Ask: what are we trying to manage? A drop may be useful, but a bottle is not a diagnosis. The answer may require a closer look at the symptom pattern, eye surface, eyelids and oil glands. Exposure and other conditions may also matter. Until those pieces are considered, the reason for short-lived relief may remain unclear.

Persistent symptoms in Geelong?

Geelong Eye Health offers dedicated dry-eye assessments in Geelong West. Bring the drops or products you already use so we can understand what you have tried and what happens next.

Frequently asked questions

Questions about drops and dry-eye assessment

Why are my eye drops not working—or only helping for a few minutes?
Natural tears are a complex living fluid. A bottle can replace only selected functions or ingredients. Drops may improve comfort, but the benefit can be brief when another problem remains. That problem may involve the tear film, eyelid oil glands, inflammation, exposure or another condition.
Why are natural tears so complex?
The TFOS DEWS II Tear Film Report describes more than 1,500 identified tear proteins and more than 200 related peptides. Tears also contain lipids, mucins, electrolytes and metabolites. Because sampling and laboratory methods affect the totals, no single count applies to every tear sample. The useful point is that natural tears contain thousands of molecular components.
Should I stop using my eye drops?
No—not because of an online article. Drops can remain a useful part of management. Bring them to your next consultation, or bring clear photos of their labels. The optometrist can then review each product, how often you use it and how long it helps. Do not stop prescribed medicine unless the prescribing clinician advises you to.
Does needing drops mean I have dry-eye disease?
Not necessarily. Burning, grittiness, redness, watering and fluctuating blur can have several causes. Your symptoms guide the questions. Your history and examination then help distinguish dry eye from allergy, infection, exposure and other eye problems.
Can dry eye be cured?
Dry-eye care usually focuses on management rather than a permanent cure. A realistic plan may aim for fewer flares and less intrusive symptoms. It may also improve comfort or visual stability and reduce the need to keep chasing short-lived relief.
When should eye symptoms be assessed urgently?
Do not treat a sudden or marked change as routine dry eye. Seek urgent professional assessment for severe pain, pronounced redness, light sensitivity or a sudden or persistent vision change. Injury, chemical exposure and a foreign body also need urgent assessment. If symptoms are severe or sight is suddenly affected, seek emergency care rather than waiting for an online booking.
References

Clinical sources used in this article

  1. TFOS DEWS II Tear Film ReportSupports the discussion of tear-film composition.
  2. TFOS DEWS III Diagnostic Methodology ReportCurrent diagnostic framework for assessing and differentiating dry-eye disease.
  3. TFOS DEWS III Management and Therapy ReportCurrent evidence-based framework for individualised dry-eye management.
  4. TFOS DEWS III downloadable summariesPatient and clinician summaries provided by the Tear Film & Ocular Surface Society.
  5. Intrinsic Disorder in the Human Tear Proteome (2023)Supports the discussion of the large number and complexity of proteins identified in tears.

Ready to look beyond the next bottle?

Book a dedicated dry-eye assessment in Geelong West and bring the drops or products you already use.

Book a Dry Eye Assessment